Drug Discovery World

 

New Pharma Qualifications Encouraged
Aug 2010

PHARMACEUTICAL and bioscience employers are being urged to shape the new Working Higher Foundation Degree qualifications for their sector by working with an industry champion, who has been appointed to strengthen the bridge between academia and business. more...

Midatech & Monosol Patent Application
Aug 2010

Midatech Group Ltd., and MonoSol Rx, the leader in developing and manufacturing pharmaceutical films based on its proprietary PharmFilm® drug delivery technology, today announced the filing of a provisional US patent application for “Nanoparticle Film Delivery Systems.” more...

Phylogica Antimicrobial Peptide Discovery
Aug 2010

Phylogica Ltd, a public Australian drug discovery company, announced today that they have entered into an agreement with MedImmune to evaluate Phylogica’s proprietary Phylomer® peptide library for novel antimicrobial peptides. more...

Almac launch Biomarkers for biopharma
Aug 2010

Almac today announced the launch of Biomarkers for biopharma; a range of solutions specifically designed to meet the needs of the biopharma industry. more...

Ambry Genetics Announces Illumina
Aug 2010

Ambry Genetics, a global leader in genomic services, announced today that it has acquired the Illumina HiSeq 2000 Next Generation Sequencing System as well as received the first 510(K) approved Illumina BeadXpress ® Genotyping System. more...

University of Nottingham Spin-out Business
Aug 2010

A newly spun-out company from The University of Nottingham, PRECOS Ltd, has secured a multi-year contract from a major pharmaceutical company, Janssen Pharmaceutica NV. more...

ANSYS Ranked on FORTUNE 100
Aug 2010

ANSYS has been ranked number 39 on the 2010 FORTUNE 100 Fastest-Growing Companies list. The ranking includes ANSYS as the sole provider of product development software, a recognition that underscores the strategic value of engineering simulation as well as the ANSYS leadership position. more...

New Therepeutic Approach To Diseases
Aug 2010

CANCER RESEARCH TECHNOLOGY has signed an agreement with Bayer Schering Pharma AG, Germany to evaluate new leptin antagonist peptides as potential experimental treatments initially in the area of gynaecological diseases, including cancer. more...

OmscientiaTM Offer Kyratec SuperCycler
Aug 2010

Omscientia, Inc., based in Carlsbad, CA, is pleased to announce that the company has entered into a distribution agreement with Kyratec Life Science (International Sales) to offer their new and innovative line of PCR and Real-Time qPCR instruments in the United States and Canada. more...

PolyTherics move to larger premises
Aug 2010

PolyTherics Ltd, today announced it has moved to larger premises to accommodate a growing team of scientists developing biobetters and novel proteins and peptides, both in-house and in partnership with pharmaceutical and biotechnology companies. more...

Phosphagenics Appoints New Directors
Aug 2010

Phosphagenics Limited has appointed Mr Stuart James, Dr Sandra Webb and Mr Don Clarke as Non-Executive Directors to formulate and facilitate the implementation of strategies to commercialise the company’s research and development pipeline. more...

Accelrys Releases Symyx Notebook 6.5
Aug 2010

Accelrys, announced the release of Symyx Notebook 6.5. This latest Symyx electronic laboratory notebook delivers improvements supporting chemical process development, production scale-up, & administrative compliance in pharmaceutical, fine chemicals, agrochemical, and consumer products markets. more...

Sartorius & SAFC Global Partnership
Aug 2010

Sartorius Stedim Biotech, & SAFC Biosciences, announced the signing of a global partnership agreement that combines SSB’s expertise in filtration and liquid handling systems with SAFC Biosciences’ proficiency in development & manufacturing of cell culture media & downstream purification products. more...

Setback for Embryonic Stem Cell Research
Aug 2010

The Alliance for Regenerative Medicine (ARM), the advocacy voice for regenerative medicine and cell therapy, issued the following statement about the August 23, 2010 Federal District Court's ruling blocking federal funding for human embryonic stem cell research: more...

New body clock drugs
Aug 2010

Researchers funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and the Medical Research Council (MRC) have successfully used a drug to reset and restart the natural 24 hour body clock of mice in the lab. more...

ChemAxon extends chemicalize.org
Aug 2010

ChemAxon announces the addition of major new functionality in it's chemicalize.org web based service. The new features help users understand better the chemical structure with more predicted properties and a customizable layout to be of most use. more...

mobilePRO by Exco InTouch
Aug 2010

Exco InTouch, the leading provider of patient communication solutions for the pharmaceutical and healthcare sectors, announces that its new mobilePRO technology is a powerful solution that overcomes issues associated with traditional ePRO technology. more...

Genetix Granted Patent for ClonePix
Aug 2010

Genetix, a leading provider of solutions for imaging and image analysis, announces that it was granted a patent, US 7,776,584 on 17th August 2010. Aspects of this patent are incorporated into ClonePix™ FL, which is used for the screening and selection of cell lines producing biopharmaceuticals. more...

Thermo Symposium Locations and Dates
Aug 2010

Thermo Fisher Scientific Inc., announced it will host a series of Laboratory Informatics Symposiums (LIS) from September 14 to September 20 in three South African locations. more...

PharmaDiagnostics SoPRanoTM
Aug 2010

PharmaDiagnostics NV, a company developing and marketing a broadly-enabling, label-free screening technology that uniquely does not require specialized equipment, announces today the launch of its SoPRanoTM assay kit, SoPRano CA1. more...

SAFC & Novozymes extend agreement
Aug 2010

SAFC, & Novozymes Biopharma DK A/S today announced a 10-year extension of their joint agreement under which SAFC retains exclusive marketing and distribution rights for Novozymes Biopharma’s LONG®R³IGF-I growth factor used for industrial cell culture applications. more...

IDBS Acquires Quantrix
Aug 2010

IDBS, the leading worldwide provider of data management and analytics solutions to R&D and healthcare organizations, today announced that it has concluded an agreement to acquire Quantrix, an award-winning company that provides business modeling and analytics software and services. more...

Software Release from FEI
Aug 2010

FEI Company, a leading scientific instrumentation company providing electron microscopy systems for nanoscale applications across many industries, released today a set of software applications that increase the throughput and ease-of-use of its electron microscopes for biological research. more...

RJW & Partners latest appointment
Aug 2010

Pricing and market access consultants to the pharmaceutical and medical device industries, RJW & Partners, are delighted to announce the appointment of Natalie Shalet as Senior Consultant, strengthening the pricing and market access capability within the firm. more...

Eurofins MWG Operon Signs Contract
Aug 2010

Eurofins MWG Operon, international market leader and expert for custom oligonucleotide synthesis and RCUK Shared Services Centre Limited (RCUK SSC Ltd) have signed a three year contract for the supply of synthetic DNA & RNA oligonucleotides. more...

Steve Smith to head up IonFlux
Aug 2010

Fluxion has announced that Steve Smith, Ph.D., has joined its management team as head of IonFlux sales and will lead sales and application efforts for the IonFlux automated patch clamp system. Steve brings to this role over 20 years of experience in the electrophysiology and drug discovery sectors. more...

Optiform Compound Optimization Platform
Aug 2010

Catalent Pharma Solutions' Optiform compound optimization platform, a novel, solid-state and highly-automated analysis platform for salt, crystal-form, and co-crystal screening, will now be broadly available to early development scientists for the first time. more...

Robust Genetic Analysis Results...
Aug 2010

Fluidigm Corporation has announced that the Toulouse Midi-Pyrénées Genomic Platform - Genotoul INRA core facility is now providing a wide range of services on a BioMark™ System for Genetic Analysis to a diverse range of French researchers. more...

Sigma & Switchgear to Co-develop
Aug 2010

Sigma Life Science, the innovative biological products and services research business of Sigma-Aldrich, and SwitchGear Genomics, Inc. today announced a joint project to develop and distribute a novel microRNA (miRNA) target reporter system. more...

Biosearch Signs Exclusive License
Aug 2010

Biosearch Technologies, Inc., today announced that the company has licensed exclusively from the University of Medicine & Dentistry of New Jersey a Single Molecule Fluorescent in-situ hybridization technology based on detection of RNA. more...






This month's featured video

High-legibility laboratory labels from Brady
Aug 2010

Unreadable, smudged or faded labels represent a fatal flaw in a laboratory data trail. Brady labelling systems, developed by the corporation’s own research teams, provide comprehensive solutions to legibility problems and ensure the integrity of sample identities. more...

University Researchers Adopt IonFlux 16
Aug 2010

Fluxion Biosciences, Inc. announced today that the Ohio State University Department of Pharmacology has purchased the IonFlux 16, the first high throughput automated patch clamp instrument of its kind geared towards the academic researcher. more...

GDDIS 2010
8-9 November

The Annual GDDIS is the leading R&D meeting for decision makers, scientific leaders and strategists. It is the only two day gathering dedicated to both real technology innovation & strategy across the entire R&D realm. more...

CHI’s Inaugural Beyond Sequencing
22-23 June

This year’s event will focus on efficient utilization of your Next-Generation Sequencng (NGS) platform. Sessions at Beyond Sequencing: Strategies for Success will cover common bottlenecks, case studies, real-world experiences and solutions from experienced users. more...

Progress in the implementation of Label-Free Dectetion - part 1: cell-based assays
Fall 2008

Overall it remains unclear whether label-free will break into main stream cell-based lead discovery or will mostly fill the gaps that other technologies do less well? more...

Natural product pharmaceuticals - the third generation
By Dr Melanie McCullagh

Compounds derived from natural products have made a big impact on the pharmaceutical industry. Of the 1,010 NCEs approved between January 1981 and June 2006, 43 were unaltered natural products (NPs) and a further 232 (23%) were second generation NP derivatives1. more...

The Healthcare Industry’s Evolving Role in Translational Research an Opportunity for Competitive Advantage
By Gregory Venters

During the 20th century, medical research has observed enormous advances in basic science discovery, highlighted by the sequencing of the human genome. However, we have not witnessed a corresponding success in the widespread application of these advances into medical practice more...

TECHNOLOGY, bane or bonanza for the pharmaceutical industry?
By Dr Stephen Naylor, Adam W. Culbertson and Dr Stephen J. Valentine

While the adoption of new technologies into the drug development process has often been seen as a panacea this article argues that, without a true understanding of the complexities how can we expect it to be the bonanza to the pharmaceutical industry and the cure for all its woes? more...

Microwave-Assisted Orgainc Synthesis an Enabling Technology with Disruptive Potential.
Fall 2008

Since the original publications on the benefits of conducting organic reactions in a microwave by Gedye1 and Majetich2 in the mid-80s, the uptake of this technique was sluggish at best for the next 12-14 years. more...

Recent Advances in HCS LaserR Scanning Cytometry
By Dr John Comley

Laser scanning cytometers have matured over the past decade to meet the needs of end-users for higher throughput cell analysis, to access to previously difficult applications and to keep pace with the diversity of new fluorophores, validated high content screening (HCS) assay kits and reagents now available. more...

High Throughput Screening, High Content Screening, Primary and Stem Cells
By Dr Richard M. Eglen

Over the past decade, the use of cell-based assays has accelerated in modern drug discovery. Indeed, the majority of assays in either target validation or lead identification/optimisation all now employ cell-based technologies. more...

Biologists Flirt with Models
By Gordon Webster

The enormous challenge posed by the complexity of biological systems represents a potential intellectual impasse to researchers and threatens to stall future progress in basic biology and healthcare. more...

High content screening – the next challenge: effective data mining and exploration
By Dr Kurt Zingler and Dr Stephan Heyse

The use of high content screening within HTS is growing and with many past hurdles now overcome, the need for effective tools for data analysis is becoming paramount. more...

Overview of Companion Diagnostics in the Pharmaceutical Industry
By Dr Stephen Naylor and Toby Cole

Current escalating costs of drug discovery, development and drug launch continue to concern the pharmaceutical sector. This has been compounded by the advent of personalised medicine and its associated demands for individualised products as well as the demise of the ‘blockbuster’ model. more...

Biomarker signal definition
By Dr Gordon F. Kapke and Dr Nigel Brown

Due to the numerous challenges in the industry, pharmaceutical companies are examining all aspects of the drug development process and rebuilding their
associated business models as necessary. more...

STEM CELLS for cellular therapy space
By Dr Enal S. Razvi and Dr Gary M. Oosta

This article explores the emerging market landscape vis-à-vis the use of stem cells as cellular therapeutics. For more than 40 years, hematopoietic stem cells have been utilised as cellular therapeutics in a number of malignant diseases as well as inborn genetic errors of metabolism. more...

Reshaping the landscape of cancer drug discovery and development
By Dr Paolo Paoletti

The landscape of cancer drug discovery and development is shifting – adjusting and reshaping itself in response to the huge rush of scientific knowledge more...

REAL-TIME PCR - where we are and where are we heading
By Dr Mikael Kubista

Quantitative real-time PCR is becoming mature technology for the quantification of nucleic acids. It is spreading wide outside its original use in the research laboratories, becoming preferred technology for a range of applications, many that require specialised solutions and adaptations. Integration with pre-analytical steps and post-processing operations are becoming key challenges. more...

COMPOUND PROFILING size impact on primary screening libraries
By William Downey, Cindy Liu and Dr Jennifer Hartigan

A recent report examines the trends in utilisation of compound libraries, as well as the impact of profiling on the size of screening decks. The drivers for choosing between large or focused libraries may be different, but the ultimate goal remains the same: improve drug discovery. more...

Removal of Contaminating Genomic DNA in QRT-PCR using a Shrimp Nuclease
Nicky Quipse, Saima Naveed Nayab and Ian Kavanagh

DNA contamination can often occur in quantitative reverse transcription – polymerase chain reactions (QRT-PCR), and should be removed in order to avoid false positive results. more...

The Effect of Amplicon Charcteristics on the success of Fast QPCR
Gerwyn Jones, Sryana Kapavaparu, Saima Nayab and Ian Kavanagh

Employing fast QPCR cycling protocols is a simple and effective way of maximising throughput by reducing run durations. Fast cycling protocols can easily be achieved by reducing the temperature step dwell times. more...

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